What should I check if column pressure increases?

Check mobile-phase preparation, filters, tubing, guard column, sample cleanliness and permitted flow conditions before evaluating the analytical column.

What can cause poor peak shape?

Possible causes include unsuitable mobile phase, sample overload, connection dead volume, contamination or inappropriate operating conditions.

When should I contact technical support?

Contact support when the issue persists after basic system and method checks, and provide complete chromatographic details.

Benson Polymeric

Troubleshooting

Practical checks for backpressure, retention drift, peak shape and contamination.

High backpressure

Check solvent filters, degassing, tubing, injector, frits and the guard column. Bypass components one at a time to isolate the restriction before acting on the analytical column.

Retention drift

Confirm mobile-phase preparation, temperature stability, equilibration, ionic-form compatibility and sample matrix consistency.

Broad or split peaks

Inspect injection solvent strength, sample overload, extra-column volume, dead volume, fittings, contamination and detector settings.

Poor resolution

Verify the installed part number, ionic form, cross-link family, column direction, temperature control and method parameters.

Ghost peaks and baseline drift

Run blanks, inspect wash solvents and carryover, evaluate detector stability, and replace contaminated mobile phase or guard material as appropriate.

Cleaning and storage

Use only procedures supported for the selected Benson ionic form. Avoid improvised cleaning sequences that may change resin form or damage the packing.